Advisory Board October 6, 2025
FDA is planning to approve leucovorin, also known as folinic acid, as a treatment for autism, citing a review of small studies that found the drug improved symptoms in certain patients. However, health experts say research on leucovorin is preliminary and premature claims about its efficacy could lead to “false hope” for patients.
Could leucovorin help children with autism?
Leucovorin, also known as folinic acid, is a modified version of vitamin B9 or folate. Folate is part of red blood cell production and is important to cell growth. It is also crucial during early pregnancy to reduce the risk of major brain or spine birth defects in infants.
Currently, leucovorin is approved to treat harmful side effects of certain...
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