pharmaphorum April 19, 2024
Researchers in the US have developed an artificial intelligence tool that can predict how a patient will respond to cancer treatment, bringing the concept of personalised therapy a step closer to reality.
While plenty of targeted therapies are available against specific cancer mutations, only a minority of patients can benefit from them. The National Cancer Institute (NCI) team and the Sanford Burnham Prebys research organisation hope their computational approach could eventually be used systematically to match patients to the best available treatment.
Their AI platform, called PERCEPTION, focuses on the transcriptome – a collection of all the mRNAs expressed in a cell – and was trained on publicly available data taken from large-scale studies that screened drugs against cancer cell...