KevinMD February 22, 2025
Oluyemisi Famuyiwa, MD

Introduction

Endometriosis is a chronic, estrogen-dependent inflammatory disease affecting approximately 10 percent of reproductive-age women and is a leading cause of infertility. Despite its significant impact, it remains underdiagnosed and inadequately managed. This review examines the pathophysiological mechanisms linking endometriosis and infertility, current treatment strategies, and the role of dietary and lifestyle interventions in optimizing reproductive outcomes.

Endometriosis is characterized by the presence of endometrial-like tissue outside the uterine cavity, primarily on the ovaries, fallopian tubes, and peritoneum. It is associated with chronic pelvic pain, dysmenorrhea, and infertility. The condition is classified into four stages based on the extent of the disease, with advanced stages showing a significant reduction in fertility rates.

Pathophysiology of endometriosis-related infertility

Several mechanisms contribute to...

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