HealthsystemCIO.com October 8, 2025
Anthony Guerra

Eric Poon, MD, MPH, Chief Health Information Officer, Duke University Health System, described how the organization is moving AI from scattered experiments to an operating discipline aligned with enterprise strategy. Poon outlined a single intake for technology decisions with added lifecycle oversight when AI is involved, and a bias toward evidence-based scaling. He said the approach ties investments to access, quality, and margin goals while creating room to evaluate, expand, or sunset tools based on outcomes.

This interview was conducted as part of our recently published Special Report on AI

At Duke, AI initiatives flow through the same front door used for other technologies; once green-lit, a dedicated AI governance function sets guardrails for pilot design, risk tiering, and...

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