Medical Xpress September 11, 2024
The chemotherapy drug cisplatin is a lifesaver for many adults and children diagnosed with cancer, but it often causes hearing loss, a side effect that can diminish quality of life following treatment. To prevent hearing damage during cancer treatment, a University of Oklahoma researcher created a novel drug delivery system that transports medications to the inner ear.
Her studies about the promising innovation are published in the Journal of Controlled Release and the Journal of Nanobiotechnology.
When a patient receives cisplatin, the drug quickly finds its way to the cochlea, the snail-shaped organ in the inner ear. The drug is retained for months in the cochlea, where it damages the tiny hair cells that play a critical role in the...