STAT July 13, 2023
By going down to the molecular level, doctors have uncovered a way to treat tumors caused by a rare brain cancer using medicines that already exist.
Two cancer drugs — currently approved for the treatment of melanoma — were able to treat a rare type of brain cancer called PCP, or papillary craniopharyngioma, researchers reported in a study published Thursday in the New England Journal of Medicine.
In a small clinical trial, 16 patients with PCP who had not received any prior radiation therapy were given cancer drugs that target the proteins BRAF and MEK, which are both involved in cell growth. The drugs — vemurafenib and cobimetinib, both marketed by Genentech — turned out to be incredibly effective, and...
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