Dietary Intervention Shows Promise in Blood Cancers

MedPage Today December 8, 2024
Charles Bankhead

— High-fiber diets tied to improved outcomes in stem-cell transplants, slowing myeloma precursors

SAN DIEGO — Increased dietary fiber had a significant association with improved outcomes in blood cancers, according to studies reported here.

Patients undergoing allogeneic hematopoietic cell transplant (allo-HCT) had significantly better survival and a lower rate of graft-versus-host disease (GVHD) with higher levels of fiber intake. The outcomes were associated with changes in biomarkers linked to better outcomes. A second study showed improvement in biomarkers linked to progression of smoldering myeloma to the frank disease state in patients who consumed a plant-based, fiber-rich diet. Both studies were bolstered by laboratory data consistent with the clinical findings, as reported at the American Society of Hematology annual meeting.

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