Health Affairs July 11, 2024
David A. Simon, I. Glenn Cohen

In 2023, state health departments in Florida and Texas reported the first locally acquired cases of mosquito-transmitted malaria in nearly 20 years. Just nine years earlier, Zika virus, a new tropical disease that can cause birth defects when acquired by pregnant people, was discovered in Chile and subsequently migrated to Florida. Stories such as these will become more common over the next decades, with a variety of organisms migrating in response to carbon emission–caused climate change. And while “climate change may be the greatest health threat of the twenty-first century,” less attention has been paid to how climate change will alter pharmaceutical development incentives.

In this article, we use the example of tropical diseases to illustrate how climate change may...

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