MedPage Today October 9, 2023
Michael DePeau-Wilson

— Findings support efforts to develop strategies to improve mental health, author says

Depressive symptoms were associated with a higher risk for all-cause and cardiovascular disease (CVD) mortality, according to a nationally representative prospective cohort study.

Of nearly 23,700 U.S. adults, mild depressive symptoms were associated with a significantly higher risk of all-cause mortality compared with no symptoms (HR 1.35, 95% CI 1.07-1.72), as were moderate to severe depressive symptoms (HR 1.62, 95% CI 1.24-2.12), reported Zefeng Zhang, MD, PhD, of the CDC in Atlanta, and co-authors.

Significant associations were also observed for CVD mortality, with corresponding hazard ratios of 1.49 (95% CI 1.11-2.00) and 1.79 (95% CI 1.22-2.62), they detailed in JAMA Network Open.

While moderate to severe depressive...

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