Medical Xpress October 28, 2024
Investigators led by Pablo Penaloza-MacMaster, Ph.D., associate professor of Microbiology-Immunology, have discovered that administering an antibody treatment four days after mRNA vaccination enhances immune responses and vaccine efficacy in mice, according to a recent study published in The Journal of Clinical Investigation.
The findings suggest a potential strategy to advance the development of mRNA vaccines for treating infectious diseases such as HIV, coronaviruses and cancer.
During the COVID-19 pandemic, mRNA vaccines proved highly effective in preventing severe infection and death caused by SARS-CoV-2, the virus responsible for COVID-19. These vaccines employ laboratory-engineered mRNA to produce viral proteins, which then activate the body’s adaptive immune response.
While effective in reducing severe SARS-CoV-2 infections, current mRNA vaccines have exhibited limitations with immune...
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