News-Medical.Net November 24, 2024
RhoFold+ delivers a leap in RNA 3D structure prediction, combining speed and accuracy to tackle data scarcity and unlock new possibilities in drug development and synthetic biology.
In a recent study published in the journal Nature Methods, a group of researchers developed a novel method called Ribonucleic Acid (RNA) High-Order Folding Prediction Plus (RhoFold+). This deep learning-based method utilizes an RNA language model to accurately predict RNA 3D structures. This method addresses the challenges of RNA’s intrinsic structural flexibility and the scarcity of experimentally determined data.
Background
RNA molecules play a central role in molecular biology, influencing gene regulation and serving as promising targets for drug development and synthetic biology. Despite the importance of RNA structure in understanding function, the...
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