Medical Xpress January 26, 2026
Researchers from the Faculty of Engineering at The University of Hong Kong (HKU) have developed two innovative deep-learning algorithms, ClairS-TO and Clair3-RNA, that significantly advance genetic mutation detection in cancer diagnostics and RNA-based genomic studies.
The pioneering research team, led by Professor Ruibang Luo from the School of Computing and Data Science, Faculty of Engineering, has unveiled two groundbreaking deep-learning algorithms—ClairS-TO and Clair3-RNA—set to revolutionize genetic analysis in both clinical and research settings.
Leveraging long-read sequencing technologies, these tools significantly improve the accuracy of detecting genetic mutations in complex samples, opening new horizons for precision medicine and genomic discovery. Both research articles have been published in Nature Communications.
Long-read sequencing technologies capture continuous stretches of DNA and RNA, providing detailed...
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