Medical Xpress November 23, 2025
University of Texas Health Science Center at Houston

A new oral GLP-1 medication can help adults with obesity and type 2 diabetes lose more weight and improve their blood sugar levels compared to a placebo, according to findings from the ATTAIN-2 trial led by a UTHealth Houston researcher.

Obesity is a chronic health condition that can cause serious complications such as type 2 diabetes, heart disease, high blood pressure, sleep apnea, certain cancers, and more. Current GLP-1 treatments for obesity consist of daily or weekly injectable medications that come with drawbacks, including the need for cold chain distribution and storage, risk of injection site reactions, and needle-related discomfort.

The findings, published in The Lancet, found an alternative treatment for adults with type 2 diabetes and obesity: a daily...

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