MedPage Today July 15, 2024
Kristen Monaco

— Clinical disease incidence jumped after infection

COVID-19 may accelerate progression of presymptomatic type 1 diabetes in youth, a German study suggested.

Incidence of clinical type 1 diabetes nearly doubled after the pandemic started among 591 youth ages 1 to 16 known to have presymptomatic type 1 diabetes, Anette-Gabriele Ziegler, MD, of the Institute of Diabetes Research at Helmholtz Munich in Neuherberg, Germany, and colleagues wrote in a JAMA research letter.

During the prepandemic period, the incidence rate for clinical type 1 diabetes development was 6.4 (95% CI 4.9-8.2) per 100 person-years, compared with 12.1 (95% CI 10.1-14.4) in the pandemic period (P<0.001).

“A key question was whether this increase was predominantly in those children who had been infected,” Ziegler...

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