COVID-19 Had Worst Disease Outcomes Among Respiratory Viruses

Drug Topics February 1, 2025
Brian Nowosielski

In their exploration of 2 separate respiratory virus seasons, researchers examined the severity of illness for SARS-CoV-2, influenza, and respiratory syncytial virus.

During the 2022-23 respiratory virus season, patients infected with SARS-CoV-2 experienced significantly worse disease outcomes when compared with influenza and respiratory syncytial virus (RSV). While these differences were less prominent in the following season, RSV remained significantly mild and COVID-19 had increased long-term mortality outcomes throughout both seasons, according to data published in JAMA Internal Medicine.¹

“Respiratory viral illnesses caused by SARS-CoV-2, influenza, and RSV are associated with substantial morbidity and mortality in older adults and persons with chronic medical conditions,” wrote authors of the study. “In the US, influenza and COVID-19 vaccinations are recommended for all adults,...

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