Advisory Board December 16, 2025

Pregnancy could accelerate biological aging in women who have never given birth by up to 5.3 years, according to a recent study published in Obstetrics & Gynecology.

Study details

For the study, researchers screened 305 women, enrolling 75 nulliparous women — women who had never given birth before — ages 18 to 50 who were seeking obstetric or gynecologic care between 2020 and 2021. Of the 75 women, 45 were pregnant and 61 completed the study.

Blood samples were collected from the women at enrollment and again postpartum — day 1 for pregnant women or 7 months for nonpregnant women — to measure epigenetic age using 11 molecular clocks.

According to the National Institute of Aging, epigenetics can mark accurate...

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