Medical Xpress March 10, 2025
University of Florida

University of Florida researchers are addressing a critical gap in medical genetic research—ensuring it better represents and benefits people of all backgrounds.

Their work, led by Kiley Graim, Ph.D., an assistant professor in the Department of Computer & Information Science & Engineering, focuses on improving human health by addressing “ancestral bias” in , a problem that arises when most research is based on data from a single ancestral group. This bias limits advancements in , Graim said, and leaves large portions of the global population underserved when it comes to disease treatment and prevention.

To solve this, the team developed PhyloFrame, a tool that uses to account for ancestral diversity in genetic data. The goal...

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