Medical Xpress January 23, 2026
I. Edwards

Colon cancer is now the No. 1 cause of cancer deaths in Americans under 50. It claimed that spot seven years earlier than previously projected. Colon cancer deaths among people under 50 have risen roughly 1% each year since 2005, researchers reported Jan. 22 in the JAMA. That increase stands out because deaths from cancer overall have dropped sharply in younger people.

Since 1990, cancer death rates in people under 50 have fallen by 44%, the study found. Colon cancer was the only one of the five cancers most common in this age group with an increase in deaths.

“It is absolutely an outlier,” lead researcher Rebecca Siegel, senior scientific director of surveillance research at the American Cancer Society (ACS),...

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