Medical Xpress September 6, 2024
Stanford University Medical Center

Cognitive behavioral therapy, one of the most common treatments for depression, can teach skills for coping with everyday troubles, reinforce healthy behaviors and counter negative thoughts. But can altering thoughts and behaviors lead to lasting changes in the brain?

New research led by Stanford Medicine has found that it can—if a therapy is matched with the right patients. In a study of adults with both and obesity—a difficult-to-treat combination—cognitive behavioral therapy that focused on reduced depression in a third of patients. These patients also showed adaptative changes in their .

Moreover, these neural adaptations were apparent after just two months of therapy and could predict which patients would benefit from long-term therapy.

The findings add to...

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