MedPage Today February 28, 2025
— SEP-1 bundle under fire as financial penalties for lack of compliance approach
ORLANDO — Following an exhaustive literature search, researchers were unable to find compelling evidence that mandated sepsis treatment guidelines from the Centers for Medicare & Medicaid Services (CMS) were favorably associated with mortality.
Of 12 observational studies in their systematic review that addressed the relationship between mortality and compliance to the Severe Sepsis and Septic Shock: Management Bundle (SEP-1), five showed a statistically significant benefit while seven did not, reported James Ford, MD, of the University of California San Diego.
On the question of whether guideline implementation was associated with sepsis mortality, one study showed benefit and four studies did not, according to findings detailed in a...
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