AJMC November 6, 2025
Key Takeaways
- The GENEROUS Model aims to reduce Medicaid drug costs by aligning prices with international standards, launching in 2026.
- It builds on existing programs like the Medicaid Drug Rebate Program and the Cell and Gene Therapy Access Model.
- Participating manufacturers will provide supplemental rebates, and states will implement standardized coverage criteria.
- CMS seeks participation from states and drug manufacturers to ensure Medicaid pricing aligns with other developed nations.
CMS introduced the GENEROUS Model to reduce Medicaid drug costs, enhance access, and improve health outcomes for beneficiaries starting in 2026.
CMS today announced the GENErating cost Reductions fOr U.S. Medicaid (GENEROUS) Model, a new drug payment model that will aim to lower prescription drug spending in Medicaid and...







