Medscape January 15, 2025
Ted Bosworth

NEW YORK — Targeted at fundamental processes that control skin aging, several therapies are currently being tested for the promise of a regulatory-granted antiaging indication, according to an update on a potentially huge area of dermatology practice.

Across a broad array of intrinsic and extrinsic drivers of skin aging, molecular targets tested in early clinical studies promise both efficacy and acceptable safety, according to Helen He, MD, assistant professor of dermatology and director of Lasers and Cosmetic Surgery, Icahn School of Medicine at Mount Sinai, New York City.

Of the targets, inflammation might be the single most important one. It has a recurring role in driving and then preserving skin cell senescence, He said.

Aging Skin Is Largely an Inflammatory...

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