Clinical Trials Arena January 21, 2025
Robert Barrie

Whilst vaccines exist for animals, none are commercially available for human use for the mosquito-borne virus.

South African biotech Afrigen Biologics has secured a $6.2m grant from the Coalition for Epidemic Preparedness Innovations (CEPI) to develop the first mRNA-based vaccine against Rift Valley fever.

The funding will see Afrigen’s researchers work with the International Vaccine Institute (IVI) to advance the mRNA candidate through preclinical testing and into a Phase I clinical trial in humans. The trial will either be conducted in South Africa or another country affected by an outbreak of the mosquito-borne disease.

Rift Valley fever was first identified more than 90 years ago in Kenya. The disease occurs in humans after contact with infected animals, meaning pastoral farmers...

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