Medical Xpress December 10, 2025
Interrupting one function of a protein that plays a key role in cell signaling could enable the development of new cancer treatments, according to a study led by Dr. Martin Taylor at the Warren Alpert Medical School of Brown University.
Cells communicate with each other and sense their environment using protein networks called signaling pathways, said Taylor, an assistant professor of pathology and laboratory medicine who is affiliated with Brown’s Center on the Biology of Aging and Legorreta Cancer Center. The more important a pathway is for cell survival, the more likely it is to be hijacked by cancer cells. The most commonly altered pathway in cancer is PI3K–mTOR–Akt, and the team’s discovery centers on mTOR, the protein at its...
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