Eric Topol November 10, 2024

New insights on evolution, resistance, and therapies

The past 2 weeks of the journal Nature were packed with 16 new publications that have substantially advanced our understanding of cancer biology. In this issue of Ground Truths, I’ll review some of the salient points and themes from this extraordinary crop of research findings.

Mapping Cancer in 4 Dimensions With Spatial Omics

The Human Tumor Atlas Network (HTAN) is a National Cancer Institute funded initiative involving 10 research centers that began its work in 2018. Its overall mission has been to improve our understanding of how cancer originates, progresses, resists or responds to therapies via high resolution mapping of cellular and molecular processes. In particular, spatial omics (a topic I’ve reviewed here...

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