MedCity News August 29, 2024
Frank Vinluan

Repare Therapeutics is cutting discovery and preclinical work to focus on its clinical-stage cancer drugs. The most advanced program is camonsertib, whose rights Repare recently regained from Roche after the pharma giant terminated an alliance started in 2022.

Repare Therapeutics has three cancer drug candidates in the clinic and another one expected to enter Phase 1 by the end of this year. The biotech aims to ensure it has enough cash to support these programs, including the most advanced of them which recently lost its big pharma partner, so it’s implementing a corporate restructuring that cuts out preclinical and discovery work.

The corporate shakeup will cut about 25% of Repare’s workforce, mostly those involved in preclinical work, the company said...

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