Advisory Board January 14, 2026
GLP-1 drugs can help patients lose a significant amount of weight, but many regain this weight after they stop taking the medication. As this issue becomes more common, researchers are exploring ways to help patients maintain weight loss in the long term.
Weight rebounds after stopping GLP-1s
According to a new study published in The BMJ, people who stopped taking weight management drugs, including GLP-1s, typically regained the weight they lost and reversed their cardiometabolic improvements within two years.
Researchers analyzed data from 37 studies with 9,341 participants, which included randomized controlled trials, non-randomized trials, and observation analyses. The studies had an average treatment duration of 39 weeks and an average follow-up period of 32 weeks. The treatments included GLP-1s...
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