KevinMD November 3, 2023
We have a problem with current recommendations for depression treatment. Thirty-five percent of patients will not go into remission or get any relief at all from SSRIs and SNRIs. And even when it does work, it takes about six weeks to start having an effect.
The prevailing theory was that serotonin, abbreviated 5-HT, was the “satisfaction” neurotransmitter. Just as dopamine has been considered the pleasure neurotransmitter. Using selective serotonin reuptake inhibitors like Prozac leaves serotonin in the synapses longer, and this action was thought to improve mood since it helps regulate sleep, cognition, and behavior in the central nervous system.
It is important here to address a concern of SSRI use. There have been studies showing that it might trigger...
Today's Sponsors
Today's Sponsor