Building a better cancer tumor
Politico September 20, 2024
INNOVATORS
Scientists studying cancer in the lab often take biopsies of patients’ cancer cells to clone them. The process is two-dimensional: The cloned cultures are grown on a flat surface like a petri dish, so unlike cancer cells in humans that form tumors, they spread out as they grow.
While scientists have grown 3D tumors in gel or using scaffolding, those tumors aren’t consistent from lab to lab. Growing consistent 3D tumors would enable scientists to study more types of cancer, including rarer and understudied cancers.
Bill King, an engineering professor at the University of Illinois at Urbana-Champaign’s Grainger College of Engineering, leads a project funded by the Advanced Research Projects Agency for Health to figure out how to improve...