Breakthrough interactive atlas offers pathway to precision medicine for TBI patients

News-Medical.Net July 16, 2024
Dignity Health Arizona

Researchers at Phoenix’s Barrow Neurological Institute and the University of Pittsburgh have created a vast interactive atlas that may eventually help doctors use precision medicine to target treatments for traumatic brain injury (TBI) patients – and could replace the existing uniform treatment model. The study was published this week by Cell Press.

With 40-50 million new cases each year, the global incidence of TBI outstrips common neurological diseases, including stroke and Alzheimer’s disease. Effective treatments have remained elusive because each TBI is different, but treatments are not.

The atlas, the first of its kind, includes 334,376 cells and information about how they responded to TBI. The goal was to deconstruct TBIs at the molecular level, opening pathways for therapies based...

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