Medical Xpress June 2, 2025
A trial of an interactive game that trains people to alter their brain waves has shown promise as a treatment for nerve pain—offering hope for a new generation of drug-free treatments.
The PainWaive technology, developed by UNSW Sydney researchers, teaches users how to regulate abnormal brain activity linked to chronic nerve pain, offering a potential in-home, noninvasive alternative to opioids.
A recent trial of the technology, led by Professor Sylvia Gustin and Dr. Negin Hesam-Shariati from UNSW Sydney’s NeuroRecovery Research Hub, has delivered promising results, published in the Journal of Pain.
The study compared hundreds of measures across participants’ pain and related issues like pain interference before, during and after four weeks of interactive game play. Their brain activity was...







