ICT&health October 9, 2025
Scientists at the University of Rochester are using innovative brain-on-a-chip technology to better understand how the brain protects itself and how this process goes wrong in diseases such as sepsis and neurodegenerative disorders. Instead of animal testing, the researchers are using microchips with human tissue, which allow them to study what happens at the blood-brain barrier: the crucial boundary between the bloodstream and the brain.
When a patient undergoes major surgery or contracts an infection such as sepsis, the immune system can react so violently that organs, including the brain, become inflamed. This often leads to long-term cognitive problems, especially in the elderly.
Brain damage due to inflammation
In a study published in Advanced Science, Professor James McGrath’s team demonstrated...







