Medscape February 13, 2025
Pr Dominique Baudon

How long will vaccine protection last? A simple blood test may have the answer. Researchers at Stanford School of Medicine, Stanford, California, have identified a molecular signature in the blood that appears days after vaccination and predicts the durability of the immune response. Published in Nature Immunology in January, this discovery could transform vaccine development, testing, and personalization of vaccines. The study also offers insights into why some vaccines provide lifelong immunity while others lose effectiveness within months.

Vaccine Durability

A major challenge in vaccinology is ensuring long-lasting, protective immunity. Vaccine protection varies depending on the vaccine and individual. Accurately determining the duration of immunity is essential for designing effective public health strategies. Scientists have long wondered why some vaccines...

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