Inside Precision Medicine January 3, 2025
Chris Anderson

A team of researchers at Stanford Medicine has uncovered a molecular signature found in blood platelets shortly after vaccination could predict how long a person’s immune response will last. The finding, published in Nature Immunology, provides a new understanding of the factors related to vaccine durability that could eventually be used for the development of more personalized vaccination strategies.

The study, which was led by Bali Pulendran, PhD, a professor of microbiology and immunology at Stanford, builds upon research into vaccine signatures published in 2022. While this earlier study identified a “universal signature” that could predict the strength of early immune responses to vaccines, this new research focuses on predicting the longevity of immunity.

“The question of why some vaccines...

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