Andreessen Horowitz December 9, 2025
a16z New Media

The biggest problems builders will tackle in 2026, according to our partners

Our job as investors is to immerse ourselves in the ins-and-outs of every corner of the tech industry in order to understand where things are moving next. So every December, we ask our investing teams to share one big idea they think tech builders will tackle in the year to come.

Today, we’re sharing ideas from our Infrastructure, Growth, Bio + Health, and Speedrun teams. Stay tuned for takes from our other teams tomorrow.

Infrastructure

Startups tame the chaos of multimodal data

Jennifer Li

Unstructured, multimodal data has been enterprises’ biggest bottleneck and their biggest untapped treasure. Every company is drowning in PDFs,...

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