McKinsey July 18, 2024

A journalist combined storytelling and detective work to uncover his family’s cancer mystery—and what it means for the fight against the disease.

In this edition of Author Talks, McKinsey Global Publishing’s Querida Anderson chats with Lawrence Ingrassia about his book A Fatal Inheritance: How a Family Misfortune Revealed a Deadly Medical Mystery (Henry Holt and Co./Macmillan Publishers, May 2024). Ingrassia details his family’s battle with numerous cancers, spotlights the pioneers who worked tirelessly to solve the puzzle of genetic mutations, and explores the ongoing advancement in cancer research and development. An edited version of the conversation follows, and you can also watch the full video at the end of this page.

Why did you write a book about Li-Fraumeni syndrome...

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