Managed Healthcare Executive March 18, 2025
Ryan Flinn

EsoBiotec’s platform has the potential to eliminate the complex and time-consuming process for manufacturing, helping to make CAR-T cell therapies more accessible.

AstraZeneca is buying EsoBiotec for up to $1 billion for the company’s in vivo CAR-T cell drugs, or therapies that reprogram immune cells directly within patients’ bodies. Analysts say the deal highlights the pharma industry’s growing interest in this technology.

Current CAR-T cell therapies have transformed the treatment landscape for certain blood cancers, but the drugs are complex and time-consuming to manufacture and carry high price tags. They also carry weeks-long post-treatment monitoring protocols and are mostly available only at major medical centers, limiting access. In vivo approaches aim to overcome these limitations and potentially extend cell therapy...

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