MedCity News March 17, 2025
Frank Vinluan

AstraZeneca’s EsoBiotec acquisition is the latest in a series of deals struck by the pharma giant to secure a place in the next wave of cell therapies for cancer and immune-mediated diseases. EsoBiotec’s allogeneic cell therapies are made by the in vivo reprogramming of a patient’s immune cells.

AstraZeneca already has cell therapies in its pipeline, and it is now expanding its scope further with a deal to acquire EsoBiotec, a company in early clinical development with therapies made by engineering immune cells inside a patient’s body.

Under acquisition terms announced Monday, AstraZeneca will pay $425 million up front for all outstanding equity of privately held EsoBiotec. The Cambridge, England-based pharmaceutical giant could pay out up to $575 million more...

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