News-Medical.Net August 1, 2024
In a recent study published in the journal Scientific Reports, researchers leveraged the knowledge that cancers and specific types of dementia share pathophysiological underpinnings to investigate the potential dementia-risk-reducing effects of anticancer drug interventions. Their retrospective study used data from the Korea National Health Insurance Service database comprising more than 100,000 cancer patients (age = 65+) prescribed anticancer medication between January 2008 and December 2018.
Their findings reveal that two classes of anticancer drugs – molecular targeted therapies and antimetabolites – were able to reduce the risk of the most common type of dementia (dementia of the Alzheimer’s type [DAT]) but showed no risk association with the second most common type (vascular dementia [VaD]). Specific hazard ratios (HR) were reported:...
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