HealthExec January 5, 2023
Using VA healthcare records, a group of researchers found that veterans who received a third dose of Moderna (mRNA-1273) had fewer documented instances of COVID-19 infections, symptomatic infections, hospitalizations, ICU admissions, and death compared with those who received a third dose of Pfizer-BioNTech (BNT162b2).
The findings, published in the journal Nature Microbiology, used veterans’ health records to conduct a retroactive analysis representing two emulated “trials.” The first trial covered veterans vaccinated during a period representing both the Delta and Omicron waves (October 2021 through February 2022), with the following results:
Trial 1 (Delta and Omicron waves): Excess number of events over 16 weeks per 10,000 people
Documented infections: 45.4 (95% CI: 19.4, 84.7)
Symptomatic infections: 3.7 (95% CI: 2.2,...