Medical Xpress January 22, 2026
Why do some tumors spread while others remain localized? The mechanisms governing the metastatic potential of tumor cells remain largely unknown—yet understanding this is crucial for optimizing patient care.
Using cells from colon cancers, scientists at the University of Geneva (UNIGE) have pinpointed the criteria that influence the risk of metastasis, and identified gene expression signatures that can be used to assess its probability. The team then created an artificial intelligence tool (MangroveGS) capable of transforming these data into predictions for many cancers with unparalleled reliability.
Their results, published in Cell Reports, pave the way for more precise care and the discovery of new therapeutic targets.
“The origin of cancer is often attributed to ‘anarchic cells,'” explains Ariel Ruiz i...
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