Medical Xpress September 30, 2024
Promising new inroads into critical DNA testing has been forecast by Flinders University experts who have applied machine learning to DNA profiling.
From medical diagnostics to forensic tests and national security, PCR (polymerase chain reaction) DNA profiling has revolutionized high-throughput sampling this century—but little has changed since it was developed in the 1980s.
“Even a small improvement in PCR performance could have a huge impact on the hundreds of thousands of forensic and intelligence DNA samples amplified every year—notably when samples are degraded,” say experts, including Flinders University academic Dr. Duncan Taylor, from Forensic Science SA.
The new research, published in two articles in Genes, discovered significant improvements both in the quality of DNA profiling and more efficient PCR cycling...
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