Inside Precision Medicine March 19, 2025
Chris Anderson

A new artificial intelligence (AI) tool developed by researchers at the Wellcome Sanger Institute, the Institute of AI for Health at Helmholtz Munich, the University of Würzburg, and collaborators has shown it is capable of rapidly analyzing and interpreting millions of cells from a patient sample, accurately predicting molecule changes in the tissue. Dubbed the NicheCompass and developed as part of the Wellcome Sanger’s Human Cell Atlas Initiative, the tool creates a visual database that combines spatial genomic data on cell types, where they are located, and how the cells communicate with each other.

Details of NicheCompass, published in Nature Genetics, show it has the potential to determine which personalized treatments could be most effective for diseases such as cancer.

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