Medical Xpress January 2, 2026
Neoantigens are unique markers that distinguish only cancer cells. By adding B cell reactivity, cancer vaccines can move beyond one-time attacks and short-term memory to become a long-term immunity that “remembers” cancer, effectively preventing recurrence. KAIST’s research team has developed an AI-based personalized cancer vaccine design technology that makes this possible and optimizes anticancer effects for each individual.
Development of the new AI model
Professor Jung Kyoon Choi’s research team from the Department of Bio and Brain Engineering, in collaboration with Neogen Logic Co., Ltd., developed the new AI model to predict neoantigens—a core element of personalized cancer vaccine development—and clarified the importance of B cells in cancer immunotherapy. Their paper is published in Science Advances.
The research team overcame...
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