Medical Xpress September 30, 2024
A blood test that uses artificial intelligence (AI) to detect cancer-related genetic changes and protein biomarkers could help screen women for early signs of ovarian cancer, according to a study by researchers at the Johns Hopkins Kimmel Cancer Center in collaboration with several other institutions in the United States and Europe.
The study, published Sept. 30 in the journal Cancer Discovery used AI-powered analyses of DNA fragments and two protein biomarkers to identify women with ovarian cancer.
The two protein biomarkers, called cancer antigen 125 (CA-125) and human epididymis protein 4 (HE4), were previously identified as ovarian cancer biomarkers but, on their own, could not reliably detect ovarian cancer. However, combining these biomarkers with AI-driven detection of cancer-associated patterns of...