AI Enhances Breast Cancer Detection in Screening Trial

Medscape February 21, 2025
Edited by Anushree Chaphalkar

TOPLINE:

Mammography supported by artificial intelligence (AI) increased breast cancer detection by 29% compared with standard double reading and reduced screen-reading workload by 44.2%, a trial showed. Using an AI system enhanced the detection of small lymph node–negative invasive cancers without increasing false positives.

METHODOLOGY:

• Researchers included 105,934 women (median age, 53.7 years) eligible for participation in a population-based mammography screening in a randomised, controlled, parallel-group, non-inferiority, single-blinded screening accuracy trial (MASAI) conducted at four sites in Sweden between 2021 and 2022.
• Participants were randomly assigned to receive either AI-supported screening (n = 53,043) for triage and detection support or standard double reading without AI (n = 52,872).
• Researchers analysed recall rates, cancer detection, false-positive rates, positive predictive value...

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