Medical Xpress January 2, 2025
Glaucoma is a progressive eye disorder characterized by fluid buildup inside the eye, causing ocular hypertension. By 2040, it is estimated that 111.8 million people worldwide will be affected by glaucoma, potentially leading to blindness if left untreated. Currently, there are treatments available to manage ocular hypertension, but a cure for glaucoma remains elusive.
Retinal ganglion cells (RGCs) are crucial for transmitting visual signals from the eyes to the brain, and their degeneration leads to optic nerve damage, which is a hallmark of glaucoma. In recent years, scientists have focused on developing neuroprotective drugs that can rescue RGCs and restore the optic nerve pathways.
Necroptosis, a pathway responsible for programmed cell death, plays a significant role in the loss of...
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