STAT January 19, 2022
Helen Branswell

By month 25 of the Covid-19 pandemic, we all probably should have learned not to try to anticipate what the SARS-CoV-2 virus is going to do next. It has so consistently defied predictions.

But the tsunami that is the Omicron wave is tempting us all the same, in large part because of an inescapable fact: By the time it crashes, the immunological landscape in this country — and in much of the world — is going to be profoundly altered. Far more people will have some immunity to Covid-19 than was the case before the wave began. Many will have what is effectively hybrid immunity, from vaccination and infection.

As a result, some experts think we may get a bit...

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