Medscape August 20, 2024
Megan Brooks

Personalized, adaptive deep brain stimulation (DBS) can enhance the control of motor symptoms of Parkinson’s disease (PD) compared with standard DBS, new research suggests.

In a blinded randomized crossover pilot trial involving four patients, adaptive DBS reduced the time spent with motor symptoms by half and improved patients’ quality of life compared with standard DBS.

“This is the future of deep brain stimulation for Parkinson’s disease,” study investigator Philip Starr, MD, PhD, professor of neurological surgery and co-director of the University of California San Francisco (UCSF) Movement Disorders and Neuromodulation Center, said in a statement.

“Adaptive DBS represents a major breakthrough in managing the symptom fluctuations in Parkinson’s disease by tailoring stimulation in real time to patients’ specific needs,” Carina...

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