Medical Xpress December 15, 2025
Discovering effective drug combinations may now be easier thanks to a screening platform made public today by St. Jude Children’s Research Hospital scientists. Many diseases, including cancers, require combinations of drugs whose effects are more than the sum of their parts to create effective treatment regimens. However, the number of new drugs and potential combinations has exploded, making classical screening methods impractical.
To address that need, the St. Jude researchers created Combocat, a platform that combines machine learning and specialized liquid handling technology to enable larger combination screens. The platform’s capabilities were published in Nature Communications.
“The field of drug discovery has lacked a way to deal with the sheer number of potential combinations, which would require impractical amounts of...
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